Rheumatology is the medical specialty concerned with diagnosis and holistic management of people, including the elderly and children, with diseases that affect joints, muscles, and bones, including multi-system and autoimmune conditions. Rheumatic disorders include forms of arthritis, autoimmune connective tissue disease, spinal and soft tissue disorders and some metabolic bone disorders, such as osteoporosis and chronic musculoskeletal pain. Clinical practice involves pain management, reduction of inflammation, and preservation of musculoskeletal function. Rheumatology is practiced in a variety of inpatient, outpatient and community settings, including private practices, public hospitals, or in conjunction with primary care providers, research and academia, or community and allied health services. Rheumatology expertise is relevant to the clinical practice areas of general medicine, nuclear medicine, aged care, or sports medicine. Rheumatic diseases impact on patients’ lives, including their ability to work and participate in wider social/community activities. Rheumatology practice involves early diagnosis and aggressive treatment of inflammation to help prevent long-term pain and disability. It utilises clinical examination, including laboratory-based testing, and imaging techniques, to help guide an accurate diagnosis. Treatments include a range of conventional disease modifying medicines, such as anti-metabolites, ‘biological’ agents, steroids and coordination of physiotherapy and other therapies.